February Fourier Talks 2010

Dorin Comaniciu


Towards Engineering the Heart


Recent advances in cardiovascular imaging, data parsing, motion estimation and computational fluid dynamics contribute to increasingly accurate models of a patient's heart. Such models are at the core of future intervention and surgery planning, outcome prediction and assessment of cardiac disease progression. This talk presents our efforts towards comprehensive patient-specific heart models containing multiple anatomical and dynamic components. Explicit physiological constraints are captured in the modeling of the left ventricle, aorta, left atrium, pulmonary veins, mitral valve and aortic valve. We demonstrate a differential assessment of the blood flow dynamics corresponding to specific heart conditions. We discuss the complexity and challenges of heart models and also their significant potential in improving the quality of care for patients with heart disease.

We acknowledge the contributions of Siemens colleagues and academic and clinical collaborators.